Chem262.exam1.key

Chem262.exam1.key - NAME _ BIOLOGY 52/SECTION 7...

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NAME ___________________________ 1 BIOLOGY 52/SECTION 7 DEVELOPMENT- LILJEGREN Final Examination – May 2, 2006 Write your name at the top of each page. Read each question carefully before answering—i.e. read the instructions. In all answers, be as specific as possible, while respecting the amount of space allotted for each answer. Use of calculators and cell phones is prohibited during the exam. No regrades will be made on exams done in pencil. Be sure to sign and abide by the honor code pledge. ---------------------------------------------------------- 1.) (8 pts) It’s important to remember that proteins have specific jobs to do in the cell. For each protein below, indicate which of the following categories best describes its job: (Some categories may not be used.) a. Growth factor e. Secreted signal b. Transmembrane receptor f. Homeodomain transcription factor c. Membrane-bound signal g. Transmembrane channel protein d. MADS-domain transcription factor h. Transcription factor Engrailed ___________________ Igf2 ___________________ White ___________________ Pax3 ___________________ LET-23 ___________________ PISTILLATA ___________________ Delta ___________________ Ultrabithorax ___________________ 2.) (1 pt) One global mechanism of regulating gene expression involves the post- translational modification of _________________ proteins associated with DNA. 3.) (10 pts) We discussed how the fly body plan is specified by a cascade of genes during embryonic development. From earliest to latest, write out each general gene category (be specific), as well as ONE actual gene in that category selected from the following list. Porcupine Antennapedia Raspberry Butthead Bald Fushi tarazu Mastermind Bicoid Krüppel Distalless Wingless Distorted Category A gene in this category a. _________________________ ________________________ b. _________________________ ________________________ c. _________________________ ________________________ d. _________________________ ________________________ e. _________________________ ________________________
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NAME ___________________________ 2 4.) (2 pts) Which organism(s) uses DNA methylation as a mechanism to regulate gene transcription? (A) Mouse (B) C. elegans Write letter(s) here ________ (C) Zebrafish (D) Drosophila (E) All of the above 5.) (3 pts) Hunchback is normally expressed in the segments of the fly embryo that will become the head. (Circle one) Is it likely to be turned ON or OFF by high levels of Bicoid? (Circle one) In a Hunchback loss-of-function mutant embryo, a. The anterior and posterior segments of the embryo both develop into a head. b. Development proceeds normally. c. All segments are transformed into head segments. d.
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Chem262.exam1.key - NAME _ BIOLOGY 52/SECTION 7...

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