ch 19 - Chapter 19 Eukaryotic Genomes Organization...

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Chapter 19: Eukaryotic Genomes: Organization, Regulation, and Evolution MULTIPLE CHOICE 1) The condensed chromosomes observed in mitosis include all of the following structures except A) nucleosomes. B) 30-nm fibers. C) 300-nm fibers. D) looped domain. E) ribosomes. ANS: E PTS: 1 TOP: Concept 19.1 2) Under the electron microscope, unfolded chromatin resembles "beads on a string." What do the "beads" represent? A) nucleosomes B) ribosomes C) beadosomes D) molecules of DNA polymerase E) molecules of RNA polymerase ANS: A PTS: 1 TOP: Concept 19.1 3) In a nucleosome, what is the DNA wrapped around? A) polymerase molecules B) ribosomes C) mRNA D) histones E) nucleolus protein ANS: D PTS: 1 TOP: Concept 19.1 4) Which of the following statements concerning the eukaryotic chromosome is false? A) It is composed of DNA and protein. B) The nucleosome is the most basic structural subunit. C) The number of genes on each chromosome is different in different cell types. D) It consists of a single linear molecule of double-stranded DNA. E) Active transcription occurs on euchromatin. ANS: C PTS: 1 TOP: Concept 19.1 5) If a cell were unable to produce histone proteins, which of the following would be expected to occur? A) There would be an increase in the amount of "satellite" DNA produced during centrifugation. B) The cell's DNA couldn't be packed into its nucleus. C) Spindle fibers would not form during prophase. D) Amplification of other genes would compensate for the lack of histones. E) Pseudogenes would be transcribed to compensate for the decreased protein in the cell. ANS: B PTS: 1 TOP: Concept 19.1 6) Which of the following statements about histones is incorrect ? A) Each nucleosome consists of two molecules, each of four types of histone. B) Histone H1 is not present in the nucleosome bead; instead it is involved in the formation
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of higher-level chromatin structures. C) The amino end of each histone extends outward from the nucleosome and is called a "histone tail." D) Histones are found in mammals, but not in other animals or in plants. E) The mass of histone in chromatin is approximately equal to the mass of DNA. ANS: D PTS: 1 TOP: Concept 19.1 7) Why do histones bind tightly to DNA? A) Histones are positively charged, and DNA is negatively charged. B) Histones are negatively charged, and DNA is positively charged. C) Both histones and DNA are strongly hydrophobic. D) Histones are covalently linked to the DNA. E) Histones are highly hydrophobic, and DNA is hydrophilic. ANS: A PTS: 1 TOP: Concept 19.1 8) Which of the following represents an order of increasingly higher levels of organization? A) nucleosome, 30-nm chromatin fiber, looped domain B) looped domain, 30-nm chromatin fiber, nucleosome C) looped domain, nucleosome, 30-nm chromatin fiber D) nucleosome, looped domain, 30-nm chromatin fiber E) 30-nm chromatin fiber, nucleosome, looped domain ANS: A PTS: 1 TOP: Concept 19.1 9) Which of the following statements is true ? A) Heterochromatin is composed of DNA, whereas euchromatin is made of DNA and RNA.
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ch 19 - Chapter 19 Eukaryotic Genomes Organization...

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