Porphyria is a sophisticated

Porphyria is a sophisticated - Vijay Patel LS 10H 1.29.08...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Vijay Patel LS 10H 1.29.08 Porphyria is a sophisticated, unique, and intriguing disorder in humans which is caused by a lack of the enzyme activity in the heme biosynthetic pathway. Usually, most types of Porphyria are inherited although a small portion of them may be obtained as acquired diseases. Additionally, those who carry the genes for inherited porphyria do not necessarily develop the clinical disease for there is a considerable amount of interaction between the initial gene defect and the secondary acquired or environmental factors (Sassa, 2006). Clinically, Porphyria was studied in the beginning of the 20th century and by 1980, enzymatic deficiencies of all the porphyrias were described and the genes responsible for porphyria have been isolated (Nordmann and Puy, 2002). Porphyria is generally classified into three categories which are: erythropoietic porphyria, acute hepatic porphyria, and chronic hepatic porphyria (Sassa, 2006). As previously mentioned, a defunct heme biosynthetic pathway is the root of the porphyria disorder. Given the many steps and enzymes involved in the pathway, it is imperative to note that if the
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 05/03/2008 for the course LS 10H taught by Professor Olson during the Spring '08 term at UCLA.

Page1 / 2

Porphyria is a sophisticated - Vijay Patel LS 10H 1.29.08...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online