BIO 250 - Exam 1 - 2002

BIO 250 - Exam 1 - 2002 - BIOCHEMISTRY 250 FIRST...

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BIOCHEMISTRY 250 FIRST EXAMINATION Friday, October 4, 2002 This exam is worth 100 points (2 pts/min) ________________________________________________________________________ 1. _________________ 7 8. _____________________ 8 2. _________________ 9 9. _____________________ 10 3. _________________ 8 10. _____________________ 12 4. _________________ 9 11. _____________________ 10 5. _________________ 9 6. ________________ 10 7. _________________ 8 extra credit ______________ 4 TOTAL _____________________/100 7 pts 1. As a diabetic in severe DKA (diabetic ketoacidosis), patient Dianne Beatty's blood pH upon admission to the hospital was about 7.1. a) Without resorting to a calculator, determine the approximate hydrogen ion concentration of her blood, showing your reasoning and work. b) By what factor, and in which direction, does this differ from "normal" blood at a pH of 7.4? c) If the [H+] of her blood were only twice as high as it was upon hospital admission, it would be at the outside lethal limit - what pH would that correspond to? Show your work.
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9 pts 2. a) Write the equation that defines the dissociationconstant, K a , for a generic weak acid, HA. K a = b) If you are told that the pK a of the unusual weak acid HBa is 5.3, what is the approximate value of its dissociation constant? [Hint: if it were 5.0, what would K a be? Then use the trick you learned in class!] c) What is the pK a of acetic acid itself, and is HAc more or less acidic than HBa? 8 pts
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BIO 250 - Exam 1 - 2002 - BIOCHEMISTRY 250 FIRST...

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