Respiratory 3 notes

Respiratory 3 notes - Occupational Lung Disease...

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Occupational Lung Disease Pneumoconioses o Sometimes referred to as Interstitial Lung Disease or Environmental Lung Disease o Occurs as a result of exposure to organic and inorganic dust and noxious gases.  o Effects depend upon : composition of substance, concentration, stimulation of immune  response, irritating properties, duration of exposure, individual’s response. o Disease may be asymptomatic for years. o Pneumoconiosis refers to a nonneoplastic alteration of the lung resulting from inhalation of  mineral or inorganic dust. o Most common types: o Silicosis o Asbestosis o Coal Worker’s Pneumoconiosis   Silicosis o Progressive disease characterizd by nodular lesions to fibrosis (most common) o A chronic fibrotic pulmonary disease caused by inhalation of silica dust. o May occur in mining, quarrying, tunneling, glass manufacturing, stone cutting, pottery, and  manufacturing of abrasives (soaps, etc.). o Silica particles are inhaled, nodular lesions are produced throughout the lung. With the passage of  time and further exposure, the nodules enlarge and coalesce. Dense masses form in the upper  portion of the lungs, resulting in the loss of pulmonary volume. This results in restrictive lung  disease. Usually only occurs after exposure for a prolonged period of time (15 to 20 years). This  fibrotic destruction of pulmonary tissue can lead to emphysema, pulmonary hypertension, and cor  pulmonale. o Manifestations of Silicosis o Chronic: a long latency period with slow progression of symptoms such as hypoxemia, air  flow obstruction, and right sided heart failure o Acute: dyspnea, fever, cough and weight loss.  o Symptoms will be more severe in the presence of fibrosis o Management of Silicosis : Supportive, rule out other lung diseases, prevent infection,  oxygen, diuretics, bronchodilators, inhaled beta-adrenergic agonists, and anti cholinergics. The  fibrotic process is irreversible, so everything is supportive   Asbestosis o Characterized by diffuse pulmonary fibrosis from inhaled asbestos dust o Even though asbestos is now restricted, many locations still have it present in the building  materials. 1
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o Patho : the inhaled fibers enter the alveoli where they are surrounded by fibrous tissue. This  tissue obliterates the alveoli, causes the pleura to thicken and develop plaque resulting in a  restrictive disease with decreased lung volume and hypoxemia.  Characterized by diffused  interstitial fibrosis.  High risk of lung cancer. o
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Respiratory 3 notes - Occupational Lung Disease...

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