{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Blood Administration Notes

Blood Administration Notes - Blood Administration Reasons...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Blood Administration Reasons for Blood Transfusions: ► to increase circulating blood volume o after surgery, trauma or hemorrhage o using whole blood or albumin ► to increase oxygen carrying capacity o for patients with severe anemia o using Packed Red Blood Cells ► To provide selected cellular components as replacement therapy o Clotting factors, platelets, albumin, fresh frozen plasma, cryoprecipitate (Factor 8) o WBC’s for neutropenic patients Types of Blood Products ► Whole Blood 300-500 mL over 2-4 hours ► Packed Red Blood cells 200-250 ml over 2-4 hours ► Leukocyte (poor RBC) 200 ml over 2-4 hours o Prevents febrile, non-hemolytic transfusion ► Platelets 200-300 ml over 15-30 minutes ► Fresh frozen plasma (clothing factors) 200 ml over 30-60 minutes ► Cryoprecipitate 10-20 ml/unit can be infused or IV Push over 3 minutes ► WBC 400 ml over one hour ► Albumin usually 2-4 ml/minute Blood and Blood Components Commonly Used in Transfusion Therapy Whole blood Cells and plasma, 40% hematocrit Volume replacement and oxygen-carrying capacity; usually used in significant bleeding (25% or more blood loss) Packed RBCS RBCs with little plasma, 75% hematocrit; some platelets and WBC’s remain Increases RBC mass; symptomatic anemia; platelets are not functional; WBC’s may cause reaction and are not functional platelets-random Platelets, plasma, some RBCS and WBCS Bleeding due to severe loss of platelets; prevent bleeding when platelets (less than 5,000-10,000); survives less in the presence of fever, chills, infection; repeated treatment causes decrease chance of survival due to alloimmunization Platelets—single donor Used for repeated treatment; decreases alloimmunation risk by limiting exposure to multiple donors Fresh Frozen Plasma Plasma, all coagulation factors, Complement Bleeding in patients with coagulation factor deficiencies; plasmapheresis Granulocytes (pheresed) Neutrophils, lymphocytes, some RBCs and platelets Severe neutropenia Lymphocytes (WBCS), apheresed Lymphocytes Stimulate graft-vs-disease effect Cryoprecipitate Fibrinogen, AHF, von willebrand factor, fibronectin Von Willebrand’s disease, Hypofibrinoginemia, Hemophilia A 1 Antihemolphilic Factor (AHF) Factor 8 Hemophilia A Factor 9 concentrate Factor 9 Hemophilia B (Christmas disease) Factor 9 complex Factor 2, 7 9, 10 Hereditary factor 7, 9, 10 deficiency; Hemophilia A with factor 7 inhibitors Albumin 5% and 25% albumin Hypoproteinemia; burns; volume expansion by 5% to increase blood volume; 25% to decrease hematocrit IV gamma globulin IgG antibodies Hypogammaglobulinemia (IN CLL, recurrent infections); ITP; primary immunodeficiency states Antithrombin 3 concentrate...
View Full Document

{[ snackBarMessage ]}

Page1 / 9

Blood Administration Notes - Blood Administration Reasons...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon bookmark
Ask a homework question - tutors are online