cloning - P.K. Reilly GHUM 102 The History and Major...

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P.K. Reilly GHUM 102 The History and Major Breakthroughs in Cloning A Brief History of Cloning (1880-present) 1880 August Weissmann states genetic information of a cell diminishes with each cell division. 1902 Walter Sutton proves chromosomes hold genetic information. 1902 Hans Spemann divides a Salamander embryo in two and shows early embryo cells retain all the genetic information necessary to create a new organism. 1928 Hans Spemann performs first nuclear transfer experiment. 1938 German scientist Hans Spemann proposes a "fantastical experiment" to transfer one cell's nucleus into an egg without a nucleus, the basic method that would eventually be used in cloning. 1944 Oswald Avery discovers genetic information is carried by the nucleic acids of cells. 1952 Briggs and King clone tadpoles. 1953 Watson and Crick find the structure of DNA. 1958 F.C. Steward grows whole carrot plants from carrot root cells. 1962 John Gurdon clones frogs from differentiated cells. 1963 J.B.S. Haldane coins the term 'clone.' 1966 Establishment of the complete genetic code. 1967 Enzyme DNA ligase isolated. 1969 Shapiero and Beckwith isolate the first gene. 1970 First restriction enzyme isolated. 1972 Paul Berg creates the first recombinant DNA molecules.
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1973 Cohen and Boyer create first recombinant DNA organisms. 1977 Karl Illmensee claims to have created mice with only one parent. 1978
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This note was uploaded on 05/03/2008 for the course GHUM 200 taught by Professor Turner during the Spring '07 term at James Madison University.

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cloning - P.K. Reilly GHUM 102 The History and Major...

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