PPT_Chapter_40_updated - Drugs Affecting the Female Reproductive System Chapter 40 Copyright 2013 Wolters Kluwer Health | Lippincott Williams Wilkins

PPT_Chapter_40_updated - Drugs Affecting the Female...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Drugs Affecting the Female Reproductive System Chapter 40
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Drugs Used to Treat Disorders of the Female Reproductive System Estrogen and Progestins Estrogen Receptor Modulators Fertility Drugs Oxytocics Abortifacients
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Site of Action for Drugs Affecting the Female Reproductive System
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Use of Drugs Affecting the Female Reproductive System Across the Lifespan
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Estrogen Estradiol (Estrace, …) Conjugated estrogens (Premarin) Esterified estrogen (Menest) Estropipate (Ortho- Est, …)
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Estrogen Indications (cont.) Treatment of female hypogonadism & ovarian failure Prevent post-partum breast engorgement Combination contraceptives Slow bone loss in osteoporosis Palliation in certain cancers that have known receptor sensitivity
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Sites of Action of the Estrogens
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Estrogen (cont.) Caution Breast feeding, metabolic bone disease, renal insufficiency, hepatic impairment Adverse Effects GU tract Systemic effects of estrogens GI effects Drug-to-Drug Interactions Drugs that enhance hepatic metabolism Corticosteroids
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Prototype Estrogen
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Progestins Drospirenone (Yasmin, …)
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