PPT_Chapter_46_updated - Antianginal Agents Chapter 46 Copyright 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Coronary Artery

PPT_Chapter_46_updated - Antianginal Agents Chapter 46...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Antianginal Agents Chapter 46
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Coronary Artery Disease (Definitions) Atheromas Fatty tumors in the intima of the heart vessels Atherosclerosis Narrowing of the heart vessels Angina Pectoris Suffocation of the chest Myocardial Infarction Cells in the myocardium become necrotic and die
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Illustration of an atheromatous plaque (a) and thrombus of an atherosclerotic plaque (b)
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Question The patient asks the nurse to explain the type of angina he is experiencing. The nurse explains the pain is due to the imbalance of myocardial supply and demand. What type of angina does this describe? A. Unstable B. Prinzmetal s C. Stable D. Ischemic
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Answer C. Stable Rationale: Stable angina: No damage to heart muscle; basic reflexes surrounding the pain restore blood flow
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Angina Stable Angina No damage to heart muscle; basic reflexes surrounding the pain restore blood flow Unstable Angina Episodes of ischemia occur even when at rest Prinzmetal s Angina Caused by spasm of the blood vessels, not atherosclerosis
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Actions of Antianginal Drugs Improve blood delivery to the heart muscle by dilating blood vessels Increasing the supply of oxygen Improve blood delivery to the heart muscle by decreasing the work of the heart Decreasing the demand for oxygen
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Types of Antianginal Drugs Nitrates Beta-Adrenergic Blockers Calcium Channel Blockers Newer (2006) Piperazineacetamides
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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Factors Affecting Myocardial Oxygen
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