Chem - Chemicals and Leukemia? A General Discussion What is...

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Chemicals and Leukemia? A General Discussion
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What is Leukemia? Cancer of white blood cells Proliferation of a clone of immature cells
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What causes cancer? Loss of control on division of cells Something happened that caused it NOT to stop Caused by a genetic mutation in a single cell – A chemical that is a “mutagen” Block of maturation sequence
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What causes mutations? Damaged DNA Caused by certain chemicals that bind, block, split, etc., DNA Radiation (i.e., ultraviolet, medical and cosmic) causing break in DNA Viruses that inserts themselves into the sequence of DNA.
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Another Cause of Mutation More or faster cell division; therefore, more chances for damage DNA replication that activates mutation Growth hormones (i.e., estrogen and breast cancer) Constant irritation and repair (i.e., scar lung cancers) Fast growing tissue (i.e., bone cancers)
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Detecting a Carcinogen Epidemiology Geographic Some areas have high levels of liver (Asia), colon (U.S.), and
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Chem - Chemicals and Leukemia? A General Discussion What is...

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