Outline 10 Hormones and Sex

Outline 10 Hormones - Outline 10 Hormones Sex I Hormones versus Neurotransmitters Neurotransmitters released directly adjacent to the target cell

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I. Hormones versus Neurotransmitters Neurotransmitters - released directly adjacent to the target cell Hormones - carried by the blood to targets in the body Several neurotransmitters are also considered hormones: epinephrine, norepinephrine, CCK, angiotension II. Types of Hormones Amino Acid derivatives (e.g., norepinephrine, epinephrine.These are monoamines.) o These are smaller hormones o Larger class of hormones. o Typically affect cells by the same route as peptide neurotransmitters, i.e., bind to receptors on the outer cellular membrane. o Most hormones released by the hypothalamus and pituitary are peptide hormones. Steroid hormones (all steroid hormones contain 4 carbon rings) o Synthesized from cholesterol. Rather small molecules. o Molecular shapes of all steroids are pretty similar. o Fat soluble, lipid soluble…no trouble passing through cell membranes. o How they work in general Typically easily pass through cellular membranes and bind to receptors in the cell cytoplasm or the nucleus Can have both relatively fast effects (change in membrane permeability to ions) and slower effects via alterations in gene expression o Some steroid hormones: cortisol- released by adrenal gland stress hormones. corticosterone - released by adrenal gland estrogens e.g., estradiol released by gonads and by adrenal glands class of hormones androgens e.g., testosterone " " " " o Sex steroids (also called "gonadal steroids", although they are also produced in smaller quantities by the adrenals) Androgens and estrogens commonly exert their effects by increasing the synthesis of some types of RNA and proteins (i.e. by altering gene expression) Some genes activated by gonadal steroids are called "sex-limited genes", because the effects are seen more strongly in one sex than the other e.g., estrogen effects on breast development androgen effects on facial hair Other effects are not sex limited, e.g., androgen stimulates pubic hair growth in both sexes The 2 major known sex differences in sex steroid production are: females produce relatively more estrogens and males produce relatively more androgens females have major cycles of hormone production, males typically do not (at least do not have cycles spanning days)…menstrual cycle. III. Control of hormone release Pituitary Gland -- The Master Gland o Hormones released by the Posterior Pituitary release 2 primary hormones oxytocin (love hormone) Ex: prairie voles, mate for 24 hrs and lots of Oxytocin released… stay together rest of their lives…block Oxytocin, then just one
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night stand. Oxytocin…together forever…no Oxytocin, one night stand. Vasopressin aka anti-diuretic hormone?
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This note was uploaded on 05/05/2008 for the course PSY 43950 taught by Professor Jones during the Spring '08 term at University of Texas at Austin.

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Outline 10 Hormones - Outline 10 Hormones Sex I Hormones versus Neurotransmitters Neurotransmitters released directly adjacent to the target cell

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