biol 4800 class 3 summaries

biol 4800 class 3 summaries - Brett Carlin Biol 4800...

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Brett Carlin Biol 4800 Section 4 Class 3 Summaries DHEA Emily Benoit DHEA is an endogenous hormone secreted by the adrenal gland. DHEA can be converted into other steroid hormones, including estrogen and testosterone. It is the most abundant androgen secreted by the adrenal gland. DHEA first appears in the bloodstream around the age of seven. Levels peak at age 25, then steadily decline with age. DHEA levels in 70 year old individuals are usually 80% lower than peak levels.   DHEA is considered to be an anti-aging hormone because DHEA deficiencies in the elderly have been associated with many medical conditions. Possible diseases/disorders DHEA supplementation may improve are adrenal insufficiency, depression, obesity, systemic lupus erythematosus, Alzheimer’s disease, bone density, cardiovascular disease, cervical cancer, chronic fatigue syndrome, cocaine withdrawal, and critical illness. Research indicates that DHEA replacement therapy can restore serum levels to those of a 21 year old. Individuals over 40 not taking a DHEA supplement usually have serum levels below 200 mcg/dl, while many test below 100 mcg/dl. Chronic DHEA deficiency is a risk factor for developing degenerative diseases of aging. Also, DHEA supplements are widely used by athletes and body builders to boost muscle mass and burn fat, but there is little evidence to support these theories. DHEA regulates the immune system by stimulating the activity of T-cells, B- cells, and macro-phages, thus strengthening the immune system. DHEA levels tend to be low in individuals with the human immunodeficiency virus (HIV). Also, studies of men and women have shown no change in body weight, but total fat and LDL cholesterol levels did improve. Studies have been done on DHEA and aids, DHEA, blood sugar and weight management, DHEA and the brain, and DHEA and cancer. Some general side effects of DHEA may include: fatigue, nasal congestion, headache, acne, rapid/irregular heartbeat. In women the most common side effects are, abnormal menses, emotional changes, headache, and insomnia. DHEA levels peak at age 25 then decline with age, in association with increased risk of age related diseases. Many studies show that DHEA supplementation may help reduce or even prevent age associated and other diseases/disorders. Longer, more comprehensive studies need to be performed to learn the exact effects of DHEA supplementation. The best part of this presentation was the amount of research being done on the subject and how interesting it is.
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Long Lived Human Populations Steven Vutera Longevity assurance genes are variants of certain genes that allow an organism to live longer. Most longevity assurance genes already identified in lower organisms such as yeast, fruit flies and worms act to increase life spans from 40-100% and grant resistance to a particularly destructive environmental stress. If scientists could identify longevity genes in humans they might be able to develop ways to manipulate those genes
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This note was uploaded on 05/05/2008 for the course BIOL 4800 taught by Professor Laine during the Spring '08 term at LSU.

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biol 4800 class 3 summaries - Brett Carlin Biol 4800...

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