ANP1105Topic 2 - Part 2 Fall 2016 - 2.3.1 Describe the...

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2.3.1 Describe the microscopic structure of skeletal muscle fibers andexplain the cellular mechanisms of excitation-contraction (pp.279-288; 294-296)2.3.2Describe the neuromuscular junction (pp. 288-294)2.3.3Describe the contractile properties of skeletal muscle (motor unit,isotonic & isometric contractions, spatial & temporalsummation, etc) (pp. 296-301)2.3.4Associate various muscle types with their metabolism and theirspeed of contraction and rate of fatigue (pp. 301-308)2.3.5Compare the properties of smooth muscle with those of skeletalmuscle (pp. 308-314)
2.3.1.1In table form, compare and contrast skeletal, smooth andcardiac muscleCommon Features of Muscle Cellselongatedcells = musclefibers;terminology:myo-,sarco-muscle contraction depends onactin&myosinmyofilamentsSkeletal MuscleCardiac MuscleSmooth MuscleAttach to and cover bonyskeletonLongest muscle fibersStriated, voluntaryCan contract rapidly; tireseasily & must restStrong,adaptableOnly inheartStriated, involuntaryPacemakersets rate ofcontraction; neural inputcanchangerateWalls of hollow, visceralorgansNonstriated, involuntarySlow,sustainedcontractions
Muscle Functions1.Generate movement:locomotion, manipulation, blood flow & pressure,respiration, propelling of food, urine, etc..2.Maintain posture:constantly working againstgravity3.Stabilize joints:eg: shoulders, knees when moving parts of skeleton4.Generate heat:maintenance of body temperature [esp:skeletal muscle- at least 40% of body mass]Functional Characteristics of Muscle1.Excitability (Responsiveness):canreceive and respond to a stimulus”stimulususually a chemical (NT, hormone, pH)response= AP along sarcolemma + musclecontraction2.Contractility:“ability to shorten forcibly when adequately stimulated”3.Extensibility:“ability to be stretched or extended”4.Elasticity:“ability to resume resting length after being stretched”.2.3.1.2list & briefly describe 4 muscle functions as well as 4functional characteristics of muscleJ. Carnegie, U of O
2.3.1.3describe the anatomy of a skeletal muscle cell; definesarcolemma, sarcoplasm, myoglobin, myofibril, sarcoplasmicreticulum, T-tubule, actin, myosin, A & I bands, A disc, H zone, M line2.3.1.4differentiate between endomysium, perimysium and epimysiumMICROSCOPIC ANATOMY OF A SKELETAL MUSCLE FIBERlong, cylindrical cell with many oval nuclei(where?What is thesarcolemma?)muscle cell is said to be asyncytium-what does this mean??huge cells (diameters of 10-100μm & lengths in cm)sarcoplasmcontains lots ofglycogen&myoglobin-what is myoglobin??lots ofmyofibrils,extensivesarcoplasmic reticulum;T-tubulesJ. Carnegie, U of O
each muscle fiber (cell) consists of parallelmyofibrils~80% of cell volume (100s to 1000s per cell)myofilaments(actin, myosin, etc.) arranged in apattern, forming end-to-endsarcomeresWhat is endomysium? perimysium? epimysium?

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Term
Fall
Professor
CARNEGIE
Tags
J Carnegie

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