february 26 2008 discussion sheet with answers

february 26 2008 discussion sheet with answers - Below is a...

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Below is a generic ketone.  Indicate the polarity.  Indicate which part might naturally be a nucleophile and  which part might naturally be an electrophile O   carbonyl oxygen can sometimes (but not very often)be a nucleophile but the  carbonyl carbon  is  the star of the show since it is very  electrophilic . Draw the mechanism for converting a ketone to an alcohol through use of an alkyllithium reagent. KETONES AND ALDEHYDES WORK SIMILARLY, SO I HAVE GIVEN ONE EXAMPLE FOR EACH  REAGENT.   FOR ALL THE ORGANOMETALLIC REAGENTS THE REACTION STOPS ONCE THE  NUCLEOPHILE IS ADDED SINCE I GAVE NO PROTON SOURCE. ESTERS REACT WITH SOME ORGANOMETALLICS   THEY ARE REDUCED TO PRIMARY  ALCOHALS WITH LITHIUM ALUMINUM HYDRIDE AND THEY REACT WITH GRIGNARD  REAGENTS TO ULTIMATELY MAKE TERTIARY ALCOHOLS. Starting 
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february 26 2008 discussion sheet with answers - Below is a...

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