Week 9 Perfusion Notes.docx - Week 9: Perfusion Flow of...

Week 9: Perfusion
Flow of blood through arteries and capillaries, delivering nutrients and oxygen to cells and
removing cellular waste.
Impaired Profusion: blood supply being reduced or completely stopped.
 Factors for Adequate Perfusion
 Sufficient fluids (blood volume)
 Adequate blood pressure
 Patent vessels
 Adequate hydrostatic pressure and capillary permeability
 Adequate cardiac functioning- pump function
 Adequate gas exchange (O2 and CO2 exchange)
 SVR- systemic vascular resistance
 Perfusion Categories
 Central perfusion- generated by cardiac output (blood ejected by heart in 1 minute 4-6 L),
stroke volume (amount of blood ejected each contraction) SV x HR = CO, systole,
diastole, preload (end volume of amount of blood at end of diastole), and afterload (SVR)
 Too much preload = blood in lungs, enlarge heart, & HF
 Local/tissue perfusion- Arteries  Capillaries (swelling, stroke, diabetes)
 Changes in Perfusion
 Acute illness: MI, shock, stroke
 Chronic Disorders: hypertension, HF
 Conditions involving perfusion
 Neurologic- interferes w/ blood flow to brain
 Pulmonary- impairs blood flow to lungs
 Cardiovascular- impairs blood flow to heart, veins, and arteries