genetics extra credit

genetics extra credit - Frank Turchioe BIO 210 Genetics Dr....

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Frank Turchioe BIO 210 Genetics Dr. Kraus 5/2/08 Cancer research has become a huge topic of conversation and controversy over the past couple of years. One particular type of cancer that has gotten a lot of attention is breast cancer. Breast cancer rates have been increasing annually and it has been estimated that by the year 2010, there will be 1.5 million new cases worldwide. The occurrence of breast cancer is due largely to genetic predisposition (5-10% of breast cancer is due to genetic predisposition). There have been two genes that have been discovered which have been identified as susceptibility genes. These two genes are BRCA1 and BRCA2. These two genes have been discovered to significantly raise the risk of breast cancer (Loizido, Marcou, Anastasiadou, Newbold, Hadjisavvas, Kyriacou 165). Even though these genes raise the risk of developing breast cancer significantly, they are rare in the population. However, there have been new DNA variations that have been discovered that are much more common but present a smaller risk of developing breast cancer (Wade). These new DNA variations were discovered with the use of new tools for breast cancer research called chips. These chips enable up to 500,000 points of variation on the human genome to be tested simultaneously for possible connection with the disease. But to achieve statistical strength, a considerable number of patients have to be recruited. Using the chips, researchers can compare the DNA of breast cancer patients with the DNA of healthy individuals so that they can look for sites on the DNA of the human genome that seem to be associated with developing breast cancer (Wade). These new DNA variations that have been discovered are not fully understood yet so we cannot say anything about them with 100% confidence but the discoverers of these variations believe
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genetics extra credit - Frank Turchioe BIO 210 Genetics Dr....

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