Announcements Complete Escape from Planet Soma Today Begin...

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Announcements Complete Escape from Planet Soma Today Begin Neuroanatomy Ch 2 p34 to 57 Next Week: Finish Neuroanatomy, start Evolution and Development. Read the bowerbird and manakin articles and the bowerbird case study. First Exam Tue Sept 20th Office Hours M 2-3:30.
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filament : light bulb :: wick : 1. wax 2. jar 3. broom 4. candle
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1 AP Reaches Terminal 2 AP Opens voltage-gated Ca++ channels, Ca++ enters terminal 3 Ca++ mobilizes vesicles, fuse with membrane and release transmitter 4 Transmitters bind to postsynaptic receptors - EPSP or IPSP 5 EPSP or IPSP spread toward axon hillock 6 Inactivation or removal 7 Repackaged and recycled 8 Bind to autoreceptors on presynaptic cell, feedback mechanism
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Packing Neurotransmitters Small NT and neuropeptides are  synthesized at terminal Large NT synthesized in cell body then  transported down the axon via thin  filaments called microtubules. Transportation is slow - can run out
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immune system : macrophages :: nervous system : 1. astrocytes 2. neurons 3. microglia 4. Schwan cells
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Why would having a non-functioning, mutant, sodium channel in a nociceptor be bad? 1. You would always be in pain. 2. You would likely have seizures. 3. You would not be able to learn from painful experiences. 4. You would be paralyzed.
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If voltage-gated Na+ channels open at a more negative membrane potential the neuron… 1. would be initially inhibited. 2. could fire with less depolarization 3. could not reach threshold 4. could fire with very little hyperpolarization
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What result will dendrotoxin have if it blocks voltage gated K+ channels in muscles? 1. The action potential will be shortened 2. The action potential will be prolonged 3. Less neurotransmitter will be released 4. The cell will be hyperpolarized
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If astrocytes do not uptake K+ surrounding neurons, how will neuron signaling be altered?
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