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Chem Lab 7.docx - ANTACID EFFECTIVENESS BY BACK-TITRATION...

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ANTACID EFFECTIVENESS BYBACK-TITRATIONSubmitted by: Tayla CardilloPartner:Date of Submission: 11/2/21Lab Section: CHE110L-28
Purpose:The purpose of this experiment is to determine the neutralization capacity of commercial antacid tablets bythe method of back-titration.Procedure:The procedure can be found on pages 61– 66 in the “General Chemistry Laboratory Manual Fall 2021.”By Robert GrossoCalculations:# mmoles of HCl added:Trial 1:0.1044x50ml= 5.22Trial 2:0.1044x50ml= 5.22# mmoles of NaOH added:Trial: 10.1123x30ml= 3.37Trial 2:0.1123x 28.49ml= 3.19# mmoles of HCl released with sample antacid:Trial 1:5.22-3.37= 1.85Trial 2:5.22-3.19= 2.03# mmoles at active ingredient/ CaCO₃:Trial 1:1.84/2= 0.925Trial 2:2.03/2=1.015# mmoles active ingredient/g sample:Trial 1:0.925//0.25= 3.7mmoles of CaCO₃ g/sampleTrial 2:1.015/0.25= 4.06mmoles of CaCO₃ g/samplemg ingredient/g sample:Trial 1:3.7x100.09= 370.3mg CaCO₃ g/sampleTrial 2:4.06x100.09=406.7mg CaCO₃ g/samplemg at CaCO₃ /tablet:Trial 1:
370.3x1.30= 481.39mgTrial 2:406.7x1.30= 528.71mg% Composition mg CaCO₃/mg tablet:Trial 1:481.39/1300 x 100= 37.03% mg CaCO₃ tabletTrial 2:528.71/1300 x 100 = 40.67%Conclusion:The purpose of this lab was to determine the neutralize capacity of a commercial antacid tablets by usingback-titration. During this experiment there were a few errors. First error made was when measuring the

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Term
Fall
Professor
Garafalo
Tags
Mole, Chemical reaction, Pharmaceutical formulation, Excipient

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