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Pancreatic Cancer.docx - The Background of Pancreatic...

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The Background of Pancreatic cancerCecelia JohnkePopulation Health ManagementProfessor AnbarNov 15, 2022
Pancreatic CancerThe pancreas is a small, spongy organ that is located deep within the abdomen, just belowthe curve of the stomach. Although the pancreas performs a variety of complex tasks, two thingsstand out as its primary functions. It secretes hormones that, among other things, help maintainand regulate body sugar levels and produces enzymes that are helpful for food digestion (Gee,2021).A tumor is a mass of individual cells that begins to grow rapidly, abnormally, anduncontrollably; this is known as cancer, which can spread aggressively locally or through theseeding of other organs through the lymphatic or blood vessel channels. There are benign tumorsas well, which typically do not spread by colonizing other parts of the body, tend to grow moreslowly and in a more orderly manner, and tend to be less serious (Gee, 2021). The disease canemerge from essentially any sort of cell in the body. Giovanni Battista Morgagni is credited withwriting the first known description of pancreatic cancer in his 1761 publication "de Sedibus EtCausis Morborum Per Anatomen Indagatis Libri Quinque. Jacob Mendez Da Costa revisitedMorgagni's original work in 1858 and also described the first microscopic diagnosis ofadenocarcinoma, establishing pancreatic cancer as a true disease entity. This was the nextsignificant step in our understanding of the disease (Abbruzzese, 2019). Adenocarcinoma of thepancreas, the most common type of pancreatic cancer, develops when exocrine pancreatic cellsbegin to grow out of control. The exocrine glands and ducts that make up the majority of thepancreas are made up of exocrine cells. The exocrine organs make pancreatic catalysts that aredelivered to the digestive organs to assist you with processing food sources. The enzymes arereleased into ducts, which are small tubes that drain into the pancreatic duct. At the ampulla of
Vater, the pancreatic duct joins the common bile duct, which carries bile from the liver, anddrains into the duodenum, the first part of the small intestine. The proportion of endocrine cellsin the pancreas is smaller. These cells directly release important hormones into the blood, likeinsulin and glucagon, which help regulate blood sugar levels. Tumors of the neuroendocrinepancreas originate in the endocrine cells.

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