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pedigreesSpr08 - 8 Usually appears with equal frequency in...

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Pedigrees Chapter 6 Mendelian Inheritance in Humans 0. Most traits in humans are due to the interaction of multiple genes and do not show a simple Mendelian pattern of inheritance. 1. A few traits represent single-genes. 0. sickle-cell anemia, cystic fibrosis, Tay-Sachs disease, Huntington disease 2. Because we cannot do breeding experiments on humans, we rely on family studies. Pedigrees 0. Pedigrees are an orderly diagram of a family’s relevant genetic features extending through multiple generations 1. Pedigrees help us to infer if a trait is from a single gene and if the trait is dominant or recessive Symbols of a Pedigree Figure 6.2, p. 134 Pedigree of Autosomal Dominant Trait 3. Never skips a generation 4. Affected persons have as least one affected parent 5. Appear with equal frequency in men and women Pedigree of Autosomal Recessive Trait
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6. Tend to skip generations 7. More likely to appear among progeny of related individuals
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Unformatted text preview: 8. Usually appears with equal frequency in men and women Basic Properties of X-linked recessive 9. Appears more in males than females 10.Does NOT pass from father to son 11. Male passes trait to daughter, who will pass trait to ½ of her sons 12.Often skips a generation Basic Properties of X-linked Dominant 13.Both males and females affected; females tend to be affected more often 14.does not skip a generation 15.Affected fathers pass on to ALL daughters Y - linked Traits 16.only males are affected 17. passed from father to son, if father affected, ALL sons will be 18.does not skip generations Twin Studies 19.another method for studying human characteristics 20.two types of twins 1. monozygotic 2. dizygotic 21.concordance 3. the percentage of twin pairs in which both twins have a particular trait...
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