Targeting Bonds between Stereogenic sp3

Targeting Bonds between Stereogenic sp3 - H.; Jones, D. R.;...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
N O O Bn R O H R' O + N O O Bn R O H Ar O + O O Me HO Me HO Me OH Me Me Me OH Me O Me NH 2 O N O O Bn R' R OH O N O O Bn Ar R OH O O O PMP R PMBO R OH HO R OPMB O O PMP R RO NH 2 O ROH Shair Chem 215 Lecture 10: Targeting σ -Bonds Between Stereogenic sp 3 -Hybridized Carbon Centers I Wednesday, October 24, 2007 Reading Assignment: Corey & Cheng Ch 4; SANROS pp 230-231, 400-401. Partial List of Topics Discussed: Stereochemical Strategies in Synthetic Simplification: Powerful Transforms Targeting σ -Bonds Between Stereogenic sp 3 -Hybridized Carbon Centers I References: (+)-Discodermolide Smith, A. B., III; Beauchamp, T. J.; LaMarche, M. J.; Kaufman, M. D.; Qiu, Y.; Arimoto,
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: H.; Jones, D. R.; Kobayashi, K. J. Am. Chem. Soc. 2000 , 122 , 8654-8664. Smith, A. B., III; Kaufman, M. D.; Beauchamp, T. J.; LaMarche, M. J.; Arimoto, H. Org. Lett. 1999 , 1 , 1823-1826. Graphical Transform Guide: Synthesis Discussed: Partial List of Transforms Covered: Syn Diastereoselective Aldol Reaction Anti Diastereoselective Aldol Reaction Synthesis of Carbamates from Alcohols p-Methoxyphenyl Acetals from Oxidation of -Methoxybenzyl Ethers Reductive Opening of -Methoxyphenyl Acetals (+)-Discodermolide...
View Full Document

Ask a homework question - tutors are online