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Kuby Immunology

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Chapter 1 Categories of the Protection by the Immune System: 1) Recognition a. Distinguish foreign invaders from self components b. Recognizes molecular patterns of common pathogens c. Distinguish pathogens from each other using subtle chem. Differences d. “self-nonself discrimination” e. Recognizes altered host cells that may lead to cancer f. Recognition triggers effector response 2) Response a. Effector response – eliminates or neutralizes invader i. Initial recognition can lead to many effector responses b. Memory response – more rapid and heightened immune reaction upon later attack i. This is the foundation of vaccinations (educating immune system to prep for later attacks) 2 Systems of Immunity: 1) Innate Immunity a. Includes molecular and cellular mechanisms predeployed before an infection to prevent/eliminate it b. 1 st line of defense c. has “self-nonself discrimination,” not ID of diff pathogens 2) Adaptive immunity a. develops response to infection and adapts to recognize, eliminate, and remember invading pathogen b. begins few days after initial infection c. memory is key for this type of immunity History: 1) Jenner –
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  • Spring '08
  • Sanders
  • humoral immunity Antigen, Adaptive Immunity Innate, Adaptive immunity a., Vaccine Active Immunity, mediate cellular immunity

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Chapter 1 Summary - Chapter 1 Categories of the Protection...

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