Mock Cancer Biology Exam 2

Mock Cancer Biology Exam 2 - BIOL760Fall16 1 ,andyouadd1...

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BIOL 760 Fall’16 BIOL 760 - CANCER BIOLOGY EXAMINATION 2 1. Suppose you culture a petri dish with epithelial lung cells that are currently in S-phase, and you add 1  mL of 0.1 uG/mL TGF-B solution. Which of the following results best describes the fate of the epithelial  lung cells? a. The lung cells will proliferate excessively. b. The lung cells will divide at normal rate. c. Cell division will be arrested. d. DNA synthesis will be halted. 2. In a cell culture assay you transfect Ras oncogene into mouse cells, and you observe 4 foci are  produced. Suppose you co-transfect Ras oncogene + p53 with a mutation in its amino terminus into a  new culture of mouse cells. What will be the effect on the number of foci generated? 3. MDM2 is a proto-oncogene. True/False. 4. ARF2 is a proto-oncogene. True/False. 5. How would a homozygous recessive for a mutation in the E2F gene in an individual influence apoptotic  activity at the cellular level?
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  • Spring '14
  • Biology, Bcl-2, foci, f. B, lung cells, ras oncogene, cell culture assay

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