f1 - 1 Eukaryotic Gene Regulation Ch11: pp 447-491 Ch12: pp...

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Unformatted text preview: 1 Eukaryotic Gene Regulation Ch11: pp 447-491 Ch12: pp 518-529 Eukaryotic Gene Regulation transcriptional level post-transcriptional level From Egg to Organism: How and Why Genes are Regulated Together, these various types of human cells enable a person to function as a whole. Is the complete set of an organisms genes Is located mainly on chromosomes in the cells nucleus Review What is a genome? 2 The Generation of Different Cell Types Four of the many different types of human cells Figure 11.2 (a) Three muscle cel s (partial) (b) A nerve cel (partial) (c) Sperm cel s (d) Blood cel s-Each has a unique cellular structure that appropriate for carrying out its function. Do they have different genes? Do they all have the same genome?-Remember that every somatic cell in your body was produced by repeated rounds of mitosis that started with the zygote . What makes them different? Gene Regulation Cell Differentiation The only way that cells with the same genetic information can develop into cells with different structures and function is if gene activity is regulated . Cell control mechanisms must determine what genes will be turned on and which will be turned off in a particular cell.- Cell differentiation The process whereby cells become specialized in structure and function. Patterns of Gene Expression in Differentiated Cells What does it mean to say that genes are turned on or off? A gene that is turned on is being transcribed into RNA, and that message is being translated into a specific proteinThis process is known as gene expression (genotype phenotype). 2 The Generation of Different Cell Types Four of the many different types of human cells Figure 11.2 (a) Three muscle cel s (partial) (b) A nerve cel (partial) (c) Sperm cel s (d) Blood cel s-Each has a unique cellular structure that appropriate for carrying out its function. Do they have different genes? Do they all have the same genome?-Remember that every somatic cell in your body was produced by repeated rounds of mitosis that started with the zygote . What makes them different? Gene Regulation Cell Differentiation The only way that cells with the same genetic information can develop into cells with different structures and function is if gene activity is regulated . Cell control mechanisms must determine what genes will be turned on and which will be turned off in a particular cell.- Cell differentiation The process whereby cells become specialized in structure and function. Patterns of Gene Expression in Differentiated Cells What does it mean to say that genes are turned on or off? A gene that is turned on is being transcribed into RNA, and that message is being translated into a specific proteinThis process is known as gene expression (genotype phenotype). 3 Patterns of Gene Expression in Differentiated Cells The difference between cells in an organism arises from the differential expression of genes.differential expression of genes....
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This note was uploaded on 03/05/2008 for the course LIFESCI 3 taught by Professor Staff during the Fall '06 term at UCLA.

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f1 - 1 Eukaryotic Gene Regulation Ch11: pp 447-491 Ch12: pp...

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