2 Psych 15 Neuroanatomy 1 - Methods for Studying the...

Info icon This preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
Methods for Studying the Nervous System I. Stereotaxic Method —enables damage to specific brain regions A. Aspiration —removes tissue B. Radio-frequency —heat damage C. Cryogenic block —cold disrupts function D. Neurotoxins —selective for certain cells
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
II. Psycho- and Neuropharmacological Methods A. Alter behavior by giving psychoactive drugs B. Mapping receptors and neurotransmitters 1. autoradiography —radiolabeled ligands bind receptors 2. immunohistochemistry —antibodies bind neurotransmitter-related molecules
Image of page 2
Immunohistochemistry demonstrating choline acetyltransferase (ChAT), the enzyme that manufactures acetylcholine . Photomicrograph provided by Prof. Woolf .
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
3. in situ hybridization —DNA and RNA probes C. Direct measurement of neurochemicals 1. microdialysis —collects brain fluids 2. in vitro voltammetry —measures current and detects neurotransmitters on the basis of their charge ChAT mRNA, from Oh et al., 1992
Image of page 4
III. Histology of Nerve Cells A. Nissl stain —cell bodies B. Golgi stain —cells and fibers C. Myelin stain —fibers A B C From Cajal, 1909
Image of page 5

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
D.
Image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern