MCB 2007 October 5th Lecture Notes

MCB 2007 October 5th Lecture Notes - October 5th Lecture...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
October 5 th Lecture Notes: DNA and Genones (Ch. 5) The Structure and Function of DNA o James Watson and Francis Crick…1953 Nobel Prize for the discovery of the double-helix structure of DNA; suggests a possible mechanism for how DNA acts as the genetic material o a DNA molecule consists of two complementary nucleotide chains which run antiparallel to one another Chargaff’s DNA base-pairing ratios: A binds with T, C binds with G, A + T = G + C Jerry Donohue…bases exist in ketone form instead of their enol form Rosalind Franklin’s x-ray data Watson and Crick’s key insight in their model: the only way the bases would all fit together is if the two stands ran anti-parallel the double-helix is held together by hydrogen bonding between a purine (A or G) and a pyrimidine (T or C) C and G are held together by 3 hydrogen bonds…more stable than A and T (two hydrogen bonds) keto groups on T and C hydrogen bond with amino groups of A and G Strand is read from 5’ to 3’ (refers to 5 and 3 Carbons on sugar…
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 3

MCB 2007 October 5th Lecture Notes - October 5th Lecture...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online