m1 - Life Science 3 Introduction to Molecular Biology...

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Life Science 3: Introduction to Molecular Biology
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Department of Molecular, Cell, and Developmental Biology University of California, Los Angeles
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• Masters in Molecular, Cell & Developmental Biology • Bachelor of Science in Molecular Biology • Ph.D. in Molecular, Cell & Developmental Biology Drosophila Genetics to cell death regulation Cell Death in the eye • Entered UCLA as a freshman in 1994-1995 Studies at UCLA
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Syllabus Info Course Objective : In this course, we introduce the basic concepts in… -biochemistry -molecular biology and molecular genetics Examples include: protein structure and function, DNA structure and replication, transcription, RNA processing and translation, and recombinant DNA technology. LS3 integrates many different areas of science, from physics and chemistry to biology, and places special emphasis on experimental approaches to understanding molecular biology.
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Molecular Cell Biology Fifth Edition Copyright © 2004 by W. H. Freeman & Company Harvey Lodish • Arnold Berk • Paul Matsudaira • Chris A. Kaiser • Monty Krieger • Matthew P. Scott • Lawrence Zipursky • James Darnell TEXT BOOK
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• Lecture cover all of the primary course material. It should focus your reading and studying. Exams will cover both the readings and lecture. • Lectures will be posted on the web ( Blackboard website: www.lsic.ucla.edu ) Note: If I can’t post it on time (10pm the night before lecture), copies of lecture slides will be handed out during class. Lecture
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Fall 07 Tentative Lecture Outline Week # Week of Topic Chapters 0 9/24 Introduction and Overview; Life Begins with Cells; Model Organisms; A Genome perspective on Evolution Ch.1 1 10/01 Chemical Foundations: Atomic Bonds and Molecular Interactions; Macromolecules Ch. 2 2 10/08 Amino acids, Proteins-Sequence, Structure, and Function; Proteins-Sequence Homology/Protein Families/BLAST Ch. 3, Ch. 9 3 10/15 Interaction of Proteins with other Molecules; Enzymes; Biochemical Energetics ( Δ G) Ch. 2, Ch. 3 4 10/22 Regulating Protein Function, Techniques: Purifying, Detecting, and Characterizing Proteins MIDTERM 1 (October 22, 5-6:50 pm): Weeks 0- 3, inclusive Ch. 3 5 10/29 Basic Molecular Genetic Mechanisms, Structure and Function of DNA and RNA, Genome and Gene Structure; Prokaryotic Transcription Ch. 4, Ch. 10 6 11/05 Genetic Code; Prokaryotic Translation, Prokaryotic Gene Regulation Veterans Day Holiday (Friday November 12) Ch. 4 7 11/12 Eukaryotic Transcription; RNA Processing, Eukaryotic Translation Ch. 4., Ch. 12, Ch. 16 8 11/19 Eukaryotic Gene Regulation; DNA Replication I Thanksgiving Holiday (Thursday November 22) MIDTERM 2 (November 19, 5-6:50 pm): Weeks 4-7, inclusive Ch. 10, Ch. 11, Ch. 12 9 11/26 DNA Replication II, DNA Repair, Viruses Ch. 4, Ch. 23 10 12/03 Recombinant DNA Technology; Genomics; DNA Sequencing and Analysis Ch. 9, Ch. 10 11 12/10 FINAL EXAM (December 12, 6:30-9:30 pm) Comprehensive
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Discussion Section • TA’s will clarify points from the lectures/readings/labs.
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m1 - Life Science 3 Introduction to Molecular Biology...

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