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Nondisjunction Disorder - Turner’s syndrome.pdf -...

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Nondisjunction Disorder - Turner’s syndromeBy:Mikneiah Jezreel BallaoGenetic Basis:This nondisjunction only affects the female population. It is a cause of a missingor partially missing X chromosome. Turner's syndrome is a rare genetic disorder that onlyaffects "approximately 1 female in 2,000-2,500 live female births. It is estimated that more than70,000 women and girls in the United States have Turner syndrome". According to the MayoClinic, there are four types of genetic changes in Turner's syndrome. The first one is calledMonosomy.This type of Turner's syndrome causes the patient to not have a complete Xchromosome, possibly because of an error in thefather's sperm or the mother's egg. Monosomy is thecommon type of TS, affecting only around 1 in every2,000 to 2,500 births of a biological female andestimating that 70,000 women and girls living in theU.S. have TS..The second type is calledMosaicism,also known asMosaic Turner syndrome. Accordingto Mayo Clinic, this type is "An error occuring in celldivision during early stages of fetal development.This results in some cells in the body having twocomplete copies of the X chromosome. Other cellshave only one copy of the X chromosome.". Thethird type of Turner's syndrome isX chromosomechanges. This type is when the X chromosome iseither completely missing or changed. This error canoccur in the sperm or egg, with all cells having onecomplete and one altered copy. The last type is called theY chromosome material. This typehas the slightest chance someone might get it. Mayo Clinic explained this: "some cells have one

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Term
Winter
Professor
Smith
Tags
Genetic disorder, Turner syndrome, amniocentesis

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