1151088042 - TLC Analysis of Analgesics 2100L/2211L Thin...

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TLC Analysis of Analgesics 2100L/2211L Thin Layer Chromatography (TLC) is a very common and versatile analysis technique. TLC can be used to check the progress of a reaction, to determine the purity of a compound and even aid in the identification of a compound or mixture. In this experiment you will use TLC to identify the active ingredients in some commercial analgesics. You should read Section T7 in the lab manual for a thorough explanation of TLC. O OH O O N H O H O O OH N N N N O O Acetylsalicylic Acid Acetaminophen Ibuprofen Caffeine Safety: Spotting capillaries are made of very fine glass and should be handled with care and disposed of properly. Procedure: At the beginning of lab, your TA should grind a tablet of each commercial analgesic in separate labeled mortars. Place a very small amount of each sample into four separate test tubes. Add 1 mL of 50:50 dichloromethane/ethanol to each test tube to dissolve the samples. On a 25 mm x 50 mm TLC plate, draw a line about one centimeter from the edge
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This note was uploaded on 05/08/2008 for the course CHEM 2212 taught by Professor Habbard during the Spring '08 term at University of Georgia Athens.

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1151088042 - TLC Analysis of Analgesics 2100L/2211L Thin...

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