Quiz 3 study guide HESC 401 - HESC 401 Study Guide for Quiz...

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HESC 401 Study Guide for Quiz 3 on chapters 5 and 6 In addition to studying the weekly objectives posted online, the question below will provide an additional guide for the quiz. Please remember to read the chapters, the lectures and memorize the concepts below. Also, completing the questions in the back of the book will help as well. Self-testing is a really great way to prepare for the quiz. 1. Define sensitivity, specificity, PPV, and NPV Sensitivity- ability of the test to identify correctly those who have the disease (component of validity) Specificity- ability of the test to identify correctly those who do not have the disease (component of validity) PPV- 2. Why does where you set a cut-point for a screening test matter? What happens if you set the cut-point too low or too high? When reviewing and understanding concepts of screening, relate it to a known screening test, such as a blood glucose test or cholesterol test. Review the handout posted, Lecture 5, slide 10 Cut point too low, then you will have fewer false negative, but there will be too many false positives of those who don’t have the disease If you set the cut-point too high, then we’ll accurately record those who don’t have the disease but we will miss many of those who have the disease If we increase the sensitivity by lower the cutoff level, we decrease specificity 3. Know how to set up a 2 x 2 table for screening tests, including the True Positive and True Negative “cells”. Know how to calculate sensitivity and specificity. Review the example posted and lecture 5, slide 5 and 6.
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TRUE CHARACTERISTICS IN THE POPULATION With Disease Without Disease e 4. What are issues with false positives and false negatives? The issue of false negatives is a problem as well. If a person has the disease, but is erroneously informed that the test result is negative, and if the disease is a serious one for which effective intervention is available, the problem is critical.
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