Unformatted text preview: 3. ↑ Cell Migration 4. ↑ MHC expression for improved T-cell recognition of pathogen * In pathogen-infected macrophage/dendritic cells, TLR signaling leads to processing and presentation of pathogen for T-Cell recognition NF-kB Function Nf-kB acts as a transcription factor for genes necessary for the effector functions of innate immunity and adaptive immunity ● Binds to antibody genes ● Generate cytokines, adhesion molecules ● May induce changes in MHC ● Involved in T/B cell signal transduction pathways...
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- Spring '08
- TLR SIGNALING, TLR Cactus, triggers Drosophila Homologs, Systemic TLR