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Unformatted text preview: milk Distribution of various Ig isotypes in body fluids serum secretions IgM IgG IgA IgE Relative amount Ig *IgD is not free floating, it's membrane-bound Disulfide bonds Important Characteristics ● IgM- 1 st isotype produced in response to infection ● IgA- most secreted Ig ● IgG- most prevalent Ig in serum ● IgE- levels low until parasitic infection ● IgG is important for complement activation, opsinization, and anti-body dependent cytotoxicity ● IgM good at complement activation ● IgE induced mast cell/basophil degranulation— involved in allergies...
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This note was uploaded on 05/06/2008 for the course MCB 150 taught by Professor Coscey during the Spring '08 term at University of California, Berkeley.
- Spring '08