Antibody effector mechanisms

Antibody effector mechanisms - enhance phagocytosis...

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Antibody Effector Mechanisms Antibody-Dependent Cellular Toxicity (ADCC) NK Cells can directly bind to antibody-bound pathogen/target and cause the apoptosis of those cells Neutralization In some situations binding to a pathogen/molecule can prevent its direct pathogenesis Opsinization By antibodies binding to the pathogen, macrophages can bind to the Fc portion and
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Unformatted text preview: enhance phagocytosis Complement-Activation The complement system proteins bind to a bacterium and open pores in its membrane through which fluids and salt move, swelling and bursting the cell. The binding of antibodies can activate the complement proteins...
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This note was uploaded on 05/06/2008 for the course MCB 150 taught by Professor Coscey during the Spring '08 term at University of California, Berkeley.

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