patho week 5 discussion #2 - Week 5 Main Discussion Post#2 Anaphylactic Shock Physiologic Progression Anaphylaxis is a severe life-threatening allergic

patho week 5 discussion #2 - Week 5 Main Discussion Post#2...

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Week 5 Main Discussion Post #2 Anaphylactic Shock Physiologic Progression Anaphylaxis is a severe, life-threatening allergic reaction [May131]. Anaphylactic shock is the result of an extensive hypersensitivity reaction know as anaphylaxis [Hue12]. An enhanced allergic reaction triggers the release of large amounts of histamines, creating marked vasodilation [Ham14]. Once an individual is exposed to the allergen, the allergens begin a humoral immune response that results in the production of large amounts of IgE antibodies [Hue12]. Degranulation of mast cells occurs, causing the mast cells to release numerous vasoactive and inflammatory cytokines [Hue12]. Symptoms will begin almost immediately, which include anxiety, dizziness, difficulty breathing, stridor, wheezing, urticaria, swollen lips and tongue, and abdominal cramping [Hue12]. Anaphylaxis requires immediate medical attention and an injection of epinephrine. If anaphylaxis is left untreated death can occur.
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