Running head: CVI AND DVT Disorders of the Veins and Arteries Shannon Taylor Walden University Advanced Pathophysiology NURS-6501N-29 December 25, 2016
CVI and DVT Disorders of the Veins and Arteries Human bodies need a sufficient venous system to supply the organs with oxygenated blood. Without sufficient blood flow to the organs, ischemia will start to occur. Ischemia is the restriction of blood supply to the tissues, usually caused by problems with the blood vessels. Chronic venous insufficiency (CVI) and deep vein thrombosis (DVT) are two conditions that are affected by the vascular system. In this paper, I will examine the pathophysiology of each disorder, along with their similarities and differences. Risk factors will be considered, as well as treatment options. Chronic Venous Insufficiency Chronic venous insufficiency (CVI) is insufficient venous return over an extended period, usually caused by varicose veins and valvular incompetence [Hue12]. The poor venous return causes blood to pool in your legs, causing increased pressure on the walls of the veins [Hen]. “Venous hypertension, circulatory stasis, and tissue hypoxia cause an inflammatory reaction in vessels and tissue leading to fibrosclerotic remodeling of the skin and then to ulceration” [Hue12]. This disorder is fairly common, affecting 40% of the U.S. population. Poor circulation impairs the distribution of the cells and biochemicals required for the immune and inflammatory responses, leading to infection [Hue12]. Deep Vein Thrombosis Deep vein thrombosis (DVT) transpires when a blood clot forms in a deep vein, usually in the lower extremities [May141]. The triad of Virchow promotes the formation of a DVT: venous stasis (congestive heart failure, age, immobility), hypercoagulable states (malignancy, pregnancy, oral contraceptives or hormone replacement therapy), and venous endothelial damage
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