nutrition chapter 10

nutrition chapter 10 - WATER-SOLUBLE VITAMINS= 8 B vitamins...

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• Travel freely in blood • Excreted by kidneys • Not stored extensively • High turn-over rate • Deficiencies develop sooner • Generally not much toxicity B VITAMINS All 8 participate in reactions facilitating energy metabolism, mostly as COENZYMES By law, milled grains in USA must be enriched (B1,B2,B3, folate, iron) People in USA at highest risk for B-vitamin deficiency are alcoholics and elderly THIAMIN- (VITAMIN B-1) FUNCTIONS COENZYME in biochemical reactions involving removal of CO 2 (example: PDH) -Mostly carbohydrate metabolism -also branched-chain amino acid metabolism Functions in several ways in nervous system (including glucose catabolism) THIAMIN DEFICIENCY Develops in 7-10 days on thiamin-deficient diet Beriberi Weakness, apathy Loss of short-term memory Confusion Irritability Peripheral neuropathy Either edema or wasting Wernicke-Korsakoff Syndrome In alcoholics- Ataxia, double-vision, staggering gait, cross-eyes, derangement
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THIAMIN SOURCES Enriched or whole-grain products Fortified cereals Pork Orange juice Legumes Sunflower seeds Soy products RDA’S: adult males = 1.2 mg/d females=1.1mg/d Intakes : adult males = 2.0 mg/d females= 1.2mg/d Thiamin Toxicity unlikely, therefore no upper limit set RIBOFLAVIN- (VITAMIN B-2) FUNCTIONS FADH and FMN = couriers of electrons from catabolic pathways to electron transport chain for ATP synthesis RIBOFLAVIN DEFICIENCY Develops in about 2 month on a riboflavin-deficient diet. Usually seen in conjunction with other deficiencies. glossitis cracks in lips, corners of mouth dermatitis confusion RIBOFLAVIN SOURCES DAIRY Enriched or whole-grain products Fortified cereals Liver mushrooms green vegetables
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RDA’S : adult males = 1.3 mg/d females =1.1mg/d Intakes : adult males = 2.1 mg/d females = 1.5 mg/d Riboflavin Toxicity unlikely, therefore no upper limit set NIACIN- (VITAMIN B-3) FUNCTIONS NADH = courier of electrons from catabolic pathways to electron transport chain for ATP synthesis….(over 200 biochemical reactions)
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nutrition chapter 10 - WATER-SOLUBLE VITAMINS= 8 B vitamins...

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