Diabetes type 1

Diabetes type 1 - Diabetes Mellitus type 1 Diabetes Mellitus is a condition characterized by hyperglycemia and other metabolic abnormalities It is

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Diabetes Mellitus type 1 Diabetes Mellitus is a condition characterized by hyperglycemia and other metabolic abnormalities. It is caused by inadequate action of insulin because of either reduced secretion of insulin from the pancreas or because of resistance of body organs to the action of insulin. Diabetes Mellitus is divided into two categories – type 1 Diabetes and type 2 Diabetes. In this brief review I will be only talking about Type 1 Diabetes Mellitus (DM type 1). The exact etiology of DM type 1 is unknown. The most accepted theory is that it is caused by interplay of genetic, environmental and autoimmune factors. For example, a viral infection might trigger an autoimmune activation of B or T lymphocytes in a genetically susceptible host. The activation of the B cells produces antibodies called autoantibodies which target specific antigens on the ß cells of the pancreas (Insulin secreting cells) causing an Antigen – Antibody complex. This leads to the activation of different arms of the immune system like complement system and T cells which together lead to the destruction of the ß cells. This eventually results in insulin deficiency and hence hyperglycemia and DM type 1 1 . In 2005, almost 1% of the US population had DM type 1. It affects whites more than blacks. It mostly occurs in persons of northern European descent. This is because of
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 05/15/2008 for the course HLTH 311 taught by Professor Drlyon during the Spring '08 term at Towson.

Page1 / 2

Diabetes type 1 - Diabetes Mellitus type 1 Diabetes Mellitus is a condition characterized by hyperglycemia and other metabolic abnormalities It is

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online