Study questions transaminases 2021.pdf - Study questions...

Study questions transaminases
1) Transaminase
1.1 The transaminase reactions consists of two similar half-reactions that constitute
what is referred to as a ping-pong mechanism. Fill in the boxes with the correct
functional groups to reveal these two half reactions.

2.0) Decarboxylation reaction – Fill in the boxes with the correct structures.
Use arrows to show the movement of electrons in the decarboxylation
reaction.

3.0) Transaminase reactions are reversible
4.1 To drive the transaminase reaction below towards the right and recover the
amine product, the ketone co-product must be removed. Fill in the boxes that
show you understand routes by which this may be accomplished. Write out
the full name of the enzymes used for I and II.
3.1 For the above reaction I), cofactor generation is accomplished using GDH. Write
out the full name corresponding to GDH and fill in the blanks that reveal how