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BERG/STRYER VI STUDY GUIDE CHAPTER 4 1. HOMEWORK 1, 2, 4, 8, 13. Answers on p. C3, longer solutions in COMPANION . Go over Companion chapter as usual after reading Berg. This chapter is designed to convey a basic idea of the working of DNA and RNA, and the basic facts of protein synthesis. You should learn the definitions of transcription and translation (107) plus replication (DNA synthesis). DNA and RNA are polynucleotides . As with proteins, in order to understand the polymer, we have to look at the monomer. Here, the monomers are nucleotides . Each nucleotide has a "base", a sugar, and a phosphate. The nomenclature is discussed on page 109. Please learn to draw the structures of A , C , T , and G either alone or as part of a nucleotide. You should also understand the simplified " stick and P " diagrams shown in Fig. 4.7. These will be used throughout the semester. The top of the "stick" represents carbon one of the sugar, which is where the "base" attaches. The bottom of the stick is carbon 5, where the phosphate is linked by an ester bond.
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