Review_1 - *Much can be explained by a system seeking its...

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*Much can be explained by a system seeking its lowest free energy state Compartmentalization – cell membrane – separation of signals, ions, organic molecules Internal and external sides need to have bulk electroneutal, osmotic equilibrium Immediately creates a problem, because there are internal organic anions that create an osmotic imbalance. Cell solves this by excluding Na ions. Plasma membrane characteristics -composition draw lipid basics Amphipathic - fluidity ? What factors contribute to membrane fluidity? determined by cholesterol, cis double bonds ? Do you want more or less fluid membrane at cold temps? ? Do you need more or less double bonds? (more) - movement of lipids ? what movement is most restricted? (more) Flip flop Asymmetry of membrane phosphatidylserine – inside, glycolipids outside Draw glycolipid structure - permeability (of lipid membrane) ? what factors determine solute permeability? Size (nanomolecules), hydrophobicity
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Review_1 - *Much can be explained by a system seeking its...

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