Cell memory and tissue differentiation part I

Cell memory and tissue differentiation part I - Cell memory...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Cell memory and tissue differentiation part I Phase variation in Salmonella Two types of genes used, H1 and H2 H1 is when transcription factor binds to promoter region and transcription occurs normally and H2 is synthesized as there is an H1 repressor gene that represses H1 synthesis. When the DNA is inverted it’s the wrong the direction so synthesis of the opposite forms as repressor is turned off, H1 is formed. Combinatorial control of gene expression Yeast can exist in 2 haploid states. To produce offspring “a” type and Alpha type must mate produce a/alpha diploid. “a” type produces a1 protein which has no effect and “a” allele is turned on. Alpha type is turned off, haploid gene is turned on. For the Alpha haploid, the alpha2 protein binds to Mcm1 and turns off “a” type locus. Alpha1 protein binds to Mcm1 and turns on Alpha gene locus. Mcm1 have opposite function. Yeast use gene mating type loci to produce haploid or diploid genes. Gene Rearrangement at the MAT locus-an inherited cassette mechanism
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 2

Cell memory and tissue differentiation part I - Cell memory...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online