Immuno_I_S08

Immuno_I_S08 - Host Defenses Old Stuff: Exam 3 Exam 4 Two...

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Unformatted text preview: Host Defenses Old Stuff: Exam 3 Exam 4 Two parts New stuff = 15% Comprehensive = 10% This Week: Host Defenses Next Week: Host-Microbe Interactions and Epidemiology Last Week: Pathogens Host Defenses Innate vs Acquired Innate: no memory Acquired: memory Line of division is artificial Innate and acquired strongly interact Innate Immunity First – line defense Cells of the immune system Cell communication Sensor systems Phagocytosis Inflammation Interferons Fever First – line defense Physical barriers Antimicrobial substances Normal flora Table 15.01a Table 15.01b Anatomical barriers Figure 15.1 Figure 15.3 Cells of the immune system Granulocytes Mononuclear phagocytes Lymphocytes Granulocytes Table 15.2 Lymphocytes Figure 15.4 Cell communication Surface receptors Cytokines Adhesion molecules Surface receptors Ligand Signal response - chemotaxis Specific Cytokines Table 15.3 Adhesion molecules Allow cells to adhere to other cells Ex. Endothelial cells bind to phagocytic cells Slow down phagocytic cell movement Sensor systems Toll – like receptors Complement system Classical pathway Alternate pathway Toll – like receptors (TLRs) Figure 15.6 Complement system Figure 15.7 Phagocytosis Process of phagocytosis Macrophages Neutrophils Process of phagocytosis Figure 15.9...
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This note was uploaded on 05/19/2008 for the course BIOL 275 taught by Professor Sandoz/shreirer during the Spring '08 term at UMBC.

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Immuno_I_S08 - Host Defenses Old Stuff: Exam 3 Exam 4 Two...

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