Odds and ends• Today: Chapter 22• Wednesday: ??• Friday: ??? And course evals• No pre-lecture quizzes left• There will be one more online quiz though – Repeat the pre-class survey that we did at the beginning. Due by Friday.• Final: 45 MC, 10 short answers, 65 points, 2 hours• Study guide/practice questions
Infectious disease• Three broad factors determine infection outcome•Virulence of Infectious agent•Dose of agent•Strength of host defense• Virulence factors: any component that increases virulence•Host defense evasion, immunosuppression, colonization, entry, etc…
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Sources of infectious agents and entry into host• Sources:• Environmental•Animal (Zoonotic diseases)•Other humans•Own microbiota•Opportunistic infection• Entry:•Various microbes have different routes of entry and colonization sites•Does not necessarily need to penetrate into host tissue to cause disease