SIADH DI - Whats going on here DI AND SIADH With discussion...

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Whats going on here?
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DI AND SIADH With discussion of dwarfism and gigantism
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Pituitary hormones.
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DI and SIADH Disturbances of Water Balance 60% to 80% of the human body is composed of water. Water content varies with age, gender, skeletal muscle mass and fat content. Osmolality is one of several factors regulating fluid balance between the intracellular and extracellular fluid compartments.
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ADH: Anti Diuretic Hormone Vasopressin Formed in the hypothalamus. Transported to the posterior lobe of the Pituitary Gland and stored. ADH is released: in response to an increase in intravascular osmotic pressure, hypovolemia, decrease in pulse pressure. And in response to fear, pain, anxiety.
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Function of ADH ADH increases the permeability of the renal distal tubule and collecting ducts to water. Less free water is excreted in urine Urine volume is decreased Concentration of urine is increased
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Diabetes Insipidus DI is a clinical condition due to a deficit of ADH or due to the kidney s resistance to the effects of ADH. DI may be central (neurogenic) or nephrogenic. DI may be a transient or a permanent condition.
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Etiologies of DI CNS disorders that damage or create pressure in the area of the hypothalamus, pituitary stalk, or posterior pituitary gland Head Injuries CNS infections Intraventricular Hemorrhage Neurosurgical Procedures: common postoperatively with resection of pituitary gland tumors, Associated with certain drugs: Ethanol, phenytoin, opiate antagonists, lithium
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Diabetes = Greek word meaning “passing water like a siphon” Aretus the Cappadocian: A 2 nd Century Doctor who first coined this term.
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