02.05 Tuesday

02.05 Tuesday - Tuesday February 5 th 2008 Recall Agonists...

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Tuesday, February 5 th , 2008 Recall: Agonists- mimic neurotransmitter Antagonists- block receptors of neurotransmitters Classification of Neurotransmitters I. Acetylcholine a. Binds to Na + , K + receptors b. Released from motor neurons (movement) to skeletal muscle, relatively large synapses c. First n’transmitter identified d. Blocker = curare, blocks receptor so the muscle doesn’t contract i. African darts ii. Used in surgery so you don’t move II. Amines a. Epinephrine (or “Adrenaline”) b. Norepinephrine (or “Noradrenaline”) c. Dopamine d. Seratonin- “feel good n’transmitter”, euphoria III. Amino Acids IV. Peptides a. Insulin- also a hormone b. Beta Endorphins- the body’s own opiates, feel good i. Mask pain, acts line morphine does Ways to stop AP’s from continuously occurring 1. Enzymes a. Acetylcholinesterase i. An enayme on acetylcholine receptors ii. Breaks down acetylcholine into acetate and choline iii. Stops continuous AP’s from occurring 2. Some n’transmitters are “called back” by their vesicles
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This note was uploaded on 05/22/2008 for the course HES 350 taught by Professor Brubaker during the Spring '08 term at Wake Forest.

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02.05 Tuesday - Tuesday February 5 th 2008 Recall Agonists...

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