iphy 3430 lecture 22

iphy 3430 lecture 22 - Glucocorticoids 1 Stimulates...

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Unformatted text preview: Glucocorticoids 1. Stimulates gluconeogenesis 2. Inhibits glucose uptake by many tissues, but not brain 3. Stimulates protein breakdown 4. Increase blood glucose concentration 5. Stimulates lipolysis 6. Anti-inflammatory and immunosuppressive 7. Responsive to stress Adrenocortical abnormalities Excess aldosterone (Conn’s syndrome) hypernatremia, hypertension Excess cortisol (Cushing’s syndrome) glucose excess, abnormal fat deposition Deficient aldosterone and cortisol (Addison’s disease) hyperkalemia, hyponatremia, hypotension 3. Growth (Somatotropic) Hormone Does not have target organ that secretes its own hormone. Controls growth after birth (via somatomedins) 1. Growth of bone 2. Growth of soft tissues 3. Stimulates protein synthesis (uptake of amino acids and inhibition of protein degredation) 4. Synergistic with thyroid hormone Non-growth aspects of growth hormone action Even in adults, growth hormone very impt....
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This note was uploaded on 05/25/2008 for the course IPHY 3430 taught by Professor Lynch,robe during the Summer '08 term at Colorado.

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iphy 3430 lecture 22 - Glucocorticoids 1 Stimulates...

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