iphy 3430 lecture 6

iphy 3430 lecture 6 - Digestion#2 Stomach 1 Store food 2...

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Digestion #2
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Stomach 1. Store food 2. Continue carbohydrate digestion 3. Begin protein digestion 4. Moisten and mechanical breakdown 5. No absorption of food, just some lipid-soluble things like alcohol, aspirin, etc.
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Secretions and stomach contractions caused by A. Pre-meal and during eating:vagus nerve B. During eating and post meal a. Local distension intrinsic nerves b. G-cell secretes gastrin
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In oxyntic mucosa Gastric pit Gastric gland Surface epithelial cells Mucosa cells Chief cells Parietal cells Enterochomaffin- like (ECL) cells In pyloric gland area G cells D cells Table 16-3, p. 596
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Stomach secretions 1. More mucus from mucus glands 2. Parietal cell a. intrinsic factor b. HCl 3. Chief cell a. pepsinogen 4. More water
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Fig. 16-11, p. 601
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Fig. 16-9, p. 597
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Benefits of HCl secretion 1. Mechanical breakdown of food 2. Activation of pepsinogen 3. Pepsin needs low pH environment for activity 4. Low pH is lethal to most pathogens
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ACCOMPLISHMENTS IN THE STOMACH 1. Some carbohydrate breakdown 2. Some protein breakdown 3. Most if not all pathogens killed 4. Chyme highly liquified
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Fig. 16-8 (1), p. 592
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INTO SMALL INTESTINE Factors that stimulate stomach emptying 1. Increased stomach distension (volume of chyme) 2. High fluidiyy of chyme Factors in duodenum that inhibit stomach emptying (signaled to stomach by intrinsic nerve plexus, secretin and cholecystokinin 1. High acidity of chyme ( low pH) 2. High fat content of chyme 3. Low osmolarity of chyme 4. Increased distension of small intestine wall caused by large volume of chyme
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SMALL INTESTINE 1. Complete enzymatic breakdown 2. Almost complete absorption of nutrients
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The presence of acidic chyme containing fats on intestinal wall causes secretion of the following: 1. Glucose-dependent insulinotropic peptide 2. Secretin 3. Cholecystokinin
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This note was uploaded on 05/25/2008 for the course IPHY 3430 taught by Professor Lynch,robe during the Summer '08 term at Colorado.

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iphy 3430 lecture 6 - Digestion#2 Stomach 1 Store food 2...

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