iphy 3430 lecture 7

iphy 3430 lecture 7 - ULCERS Protection against stomach...

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ULCERS Protection against stomach acid 1. Mucosal barrier 2. Membranes of mucosal cells impermeable to acid 3. Tight junctions between cells 4. Rapid turnover of cells
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Ulcers, cont. Causes: 1. Helicobacter pylori a. secretes urease b. flagellae help them tunnel into stomach wall c. avoid acid-producing areas of stomach 2. Alcohol, non- steroidal, anti-inflammatory drugs (aspirin, etc) 3. Stress induces overproduction of HCl
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Vomiting stimuli--> Vomiting center in medulla --> motor output --> PNS and SNS output
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Vomiting, cont. Stimuli: a. toxins in stomach b. Pressure receptors at back of throat, tongue c. elevated intracranial pressure d. Dizziness e. Emotional stress
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Vomiting, cont. Motor output: 1. contraction of inspiratory muscles (esp. diaphragm) and abdominal muscles 2. glottis and epiglottis closure 3. uvula elevated to close off nasal passages 4. jaw thrusts out, opening pharyngoesophageal sphincter PNS output: Salivation, nausea SNS output: sweating, increased heart rate
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iphy 3430 lecture 7 - ULCERS Protection against stomach...

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