iphy 3430 lecture 10

iphy 3430 lecture 10 - Circulatory System Purposes Delivery...

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Circulatory System Purposes: Delivery of O2, energy containing substrates, vitamins and other nutrients to cells; Removal of CO2, secretory products, and waste products from cells.
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Topics a. blood constituents b. transport of gases c. heart function d. blood pressure e. blood volume and lymphatic system
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Additional components of the circulatory system: Medulla vasomotor center SNS, PNS And, blood...
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Components of Blood: Cells: red blood cells, white blood cells, and platelets Plasma: water proteins a. Albumin b. globulins ( α , β , γ ) c. Fibrinogen ions glucose, amino acids wastes (urea, ammonia, creatinine, etc)
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Transport of Oxygen 3% transported dissolved in plasma 97% transported in red blood cell in association with hemoglobin
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Red blood cells Men: 5 million/ml blood Women: 4.5 million/ml blood 25-30 trillion rbc’s in total blood volume 120 day life span no nucleus, mitochondria nor ribosomes 4 heme groups (Fe plus pyrroles) + 4 globin molecules
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Hemoglobin binding on heme groups 1. O 2 2. CO on globin chains 3. CO 2 4. H+ 5. Nitric oxide (NO) 6. 2,3 biphosphoglycerate
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