iphy 3430 lecture 15

iphy 3430 lecture 15 - MUSCLE SYSTEM MUSCLE SYSTEM 1...

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MUSCLE SYSTEM
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MUSCLE SYSTEM 1. contributes to homeostasis by moving materials from one place to another (blood, food, urine, fetus) 2. contributes to energetics by using ATP for muscle contraction.
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Types Striated--Skeletal and Cardiac muscle Unstriated--Smooth muscle Other organs involved: brain, motor nerves
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Excitation-Contraction Coupling 1. Action potential from brain causes release of acetylcholine at neural muscular junction 2. ACH binds to receptor on muscle membrane, causing increased permeability of muscle membrane to Na+ 3. Increased permeability to Na+ causes action potential to occur in muscle membrane 4. Action potential spreads over entire surface of muscle membrane, down into t-tubules
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5. Action potential in t-tubules causes Ca++ to be released from vesicles on sarcoplasmic reticulum 6. Ca++ binds to troponin, causing tropomyosin to slide off active sites on actin cross-bridge binding sites 7. Exposed actin sites bind to myosin cross bridges, which were previously energized by
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This note was uploaded on 05/25/2008 for the course IPHY 3430 taught by Professor Lynch,robe during the Summer '08 term at Colorado.

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iphy 3430 lecture 15 - MUSCLE SYSTEM MUSCLE SYSTEM 1...

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